AI generated summary of Pubmed citation/abstract with PMID 38093478

https://pubmed.ncbi.nlm.nih.gov/38093478
The study found that existing blood pressure thresholds used to diagnose hypertensive disorders of pregnancy (HDP) lack sensitivity in pregnant people with sickle cell disease (SCD). The study suggests that lowering the blood pressure threshold for defining HDP may improve the identification of pregnant individuals with SCD who need increased observation, early delivery consideration, and eclampsia prophylaxis. The study analyzed data from singleton pregnancies in people with SCD delivered at two academic centers between 1990 and 2021. The study found that the systolic blood pressure (SBP) or diastolic blood pressure (DBP) thresholds that maximized sensitivity and specificity in identifying those with new or worsening proteinuria (NWP) were 120 mmHg SBP and 70 mmHg DBP. The existing BP threshold of 140/90 mmHg lacked sensitivity for both genotype groups. The study concludes that lowering the BP threshold for HDP diagnosis may benefit pregnant individuals with SCD.