AI generated summary of Pubmed citation/abstract with PMID 38093496

https://pubmed.ncbi.nlm.nih.gov/38093496
This study investigates the relationship between thyroid function and sex hormones in female German Shepherd dogs. The researchers hypothesized that estrous stage may affect thyroid function. They monitored 17 dogs throughout their estrous cycle and analyzed blood samples for thyroid hormones (TT4, fT4, TT3, fT3, cTSH), progesterone, 17-β-estradiol, triglycerides, and cholesterol. Hematological and biochemical evaluations were also performed. Results showed that TT4, fT4, and fT3 concentrations were negatively correlated with age, and TT4 concentrations were higher in estrus and diestrus stages, positively correlated with progesterone, and negatively correlated with 17-β-estradiol. Free thyroxine did not show significant variations but was positively correlated with progesterone. Canine TSH concentrations were positively correlated with 17-β-estradiol. No significant differences in thyroid hormones and cTSH concentrations were observed between diestrus during pregnancy and pseudopregnancy. The study concludes that different stages of estrus can influence the measurement of TT4 in female dogs.