“Docetaxel Reduces Metastatic Prostate Cancer Cell Viability More Effectively in 2D Monolayers Than in 3D Spheroids, Highlighting the Importance of Both Models in Therapeutic Target Discovery”

https://pubmed.ncbi.nlm.nih.gov/38095149

Docetaxel decreases metastatic prostate cancer cell viability more effectively in 2D monolayers than in 3D multicellular tumor spheroids, which better resemble early solid tumors in vivo, suggesting the importance of considering both models when searching for new therapeutic targets.