“S-Enantiomers of Certain NSAIDs Have Higher Skin Permeation Than R-Enantiomers: Ceramide Interaction and Enantioselective Permeation Mechanisms”

https://pubmed.ncbi.nlm.nih.gov/38112192

This study reveals that S-enantiomers of certain NSAIDs exhibit higher skin permeation than R-enantiomers due to stronger interactions with ceramide, providing innovative insights into the molecular mechanisms governing enantioselective permeation of drug enantiomers through the skin.