Secondary Somatosensory Cortex Modulates Pain and Thalamus Glutamatergic Innervation: Implications for Neuropathic Pain Treatment.

https://pubmed.ncbi.nlm.nih.gov/38112733

This study suggests that the secondary somatosensory cortex modulates pain through glutamatergic innervation of the thalamus, and its hyperactivity contributes to neuropathic pain, justifying potential clinical strategies targeting these corticothalamic circuits for treatment.