“Sirtuin 5-mediated deacetylation of TAZ at K54 promotes TAZ nuclear localization, CTGF expression, and melanoma development” is the title of the study. It describes the role of Sirtuin 5 in deacetylating the TAZ protein at a specific lysine residue, leading to its nuclear localization, increased expression of the connective tissue growth factor (CTGF), and ultimately, the promotion of melanoma development.