“Reduced Risk of Gastrointestinal Bleeding in Older Atrial Fibrillation Patients on Oral Anticoagulation and PPIs”

https://pubmed.ncbi.nlm.nih.gov/38114724

This study suggests that in older patients with atrial fibrillation, initiating oral anticoagulation while using proton pump inhibitors (PPIs) is associated with a reduced risk of upper gastrointestinal bleeding, particularly within the first 6 months of antivitamin K antagonist therapy.