“Activator Protein 1 Influences Clear Cell Renal Cell Carcinoma Tumorigenesis and Transcriptional Expression in Proximal Tubule Cells”

https://pubmed.ncbi.nlm.nih.gov/38114996

The activator protein 1 (AP-1) plays a crucial role in clear cell renal cell carcinoma (ccRCC) tumorigenesis, with predominant activation in cancer cells compared to proximal tubule cells, and its transcriptional expression in proximal tubule cells may be influenced by subsequent transcriptional modifications.