“HIV-1 Vif’s Direct Inhibition of Human APOBEC3 Deaminases A3G, A3F, and A3B Independent of Proteasomal Degradation”

https://pubmed.ncbi.nlm.nih.gov/38115583

The abstract reports the discovery of a direct inhibitory effect of HIV-1 Vif on human APOBEC3 deaminases A3G, A3F, and A3B, independent of the proteasomal degradation pathway, specifically through the interaction between VβBCC and the C-terminal domain of A3G.