Single-cell and spatial transcriptomics analysis identifies a subset of myofibroblastic cancer-associated fibroblasts correlating with immune suppression, desmoplastic architecture, and poor prognosis in non-small cell lung cancer

https://pubmed.ncbi.nlm.nih.gov/38115703

Single-cell and spatial transcriptomics analysis identified a subset of myofibroblastic cancer-associated fibroblasts (POSTN+ CAFs) that correlate with immune suppression, desmoplastic architecture, and poor prognosis in non-small cell lung cancer.