“Identification of New LIN28 Inhibitors: N-Biphenyl Pyrrolinones and N-Dibenzofurans as Alternatives to Salicylic Acid Moiety”

https://pubmed.ncbi.nlm.nih.gov/38116413

Researchers have identified new N-biphenyl pyrrolinones and N-dibenzofurans as potent LIN28 inhibitors, challenging the belief that a salicylic acid moiety is essential for activity, and potentially improving membrane permeability and reducing toxicity.