“Discovery and Characterization of Kinase Inhibitor CZC-54252 and Its Analogues with Potent Antiplasmodial Activity”

https://pubmed.ncbi.nlm.nih.gov/38116430

The abstract reports the discovery and characterization of a kinase inhibitor, CZC-54252, and its 39 analogues that show nanomolar inhibition against five Plasmodium falciparum kinases, with eight submicromolar inhibitors demonstrating potent antiplasmodial activity.