“5-Arylethynyl Aminothiophene Derivatives as Positive Allosteric Modulators of A1 Adenosine Receptor for Potential Drug Candidates”

https://pubmed.ncbi.nlm.nih.gov/38116442

The study identified specific 5-arylethynyl aminothiophene derivatives that act as positive allosteric modulators of the A1 adenosine receptor, with one compound also exhibiting agonist activity, offering potential as drug candidates for engaging protective A1ARs.