“Thiol-Free Copper Iodide-Catalyzed Synthesis of (Z)-β-Alkenyl Sulfides in Polyethylene Glycol”

https://pubmed.ncbi.nlm.nih.gov/38116654

This study reports a thiol-free, copper iodide-catalyzed method for the regioselective synthesis of (Z)-β-alkenyl sulfides via a three-component reaction utilizing aryl/alkyl halides, phenylacetylene, and potassium isopropylxanthate in polyethylene glycol, with the carbothionate intermediate and Z isomer formation confirmed.