“Enhancing Catalytic Activity of Thermophilic Chitinase through Residue Modification: A Rational Design Strategy for GH18 Processive Chitinases”

https://pubmed.ncbi.nlm.nih.gov/38116793

This study reveals that modifying specific conserved residues in the active site of a thermophilic chitinase enhances its catalytic activity on colloidal and crystalline chitin substrates, offering a rational design strategy for improving GH18 processive chitinases.