Monocytes from Pregnant Women Show Altered Metabolism and Enhanced Efferocytosis, Resembling Monocytes Treated with Conditioned Media from First Trimester Trophoblast Cells, Suggesting Trophoblast Contribution to Monocyte Functional Shaping during Pregnancy

https://pubmed.ncbi.nlm.nih.gov/38117266

Monocytes from pregnant women exhibit altered metabolism and enhanced efferocytosis, resembling the immunometabolic phenotype of monocytes treated in vitro with conditioned media from first trimester trophoblast cells, indicating that trophoblast cells contribute to monocyte functional shaping during pregnancy.