Home » New Synthetic Compounds from Ugi Reaction More Effectively Inhibit Enzymes Targeted in Diabetes Treatment Than Positive Control Acarbose: In Vitro and In Silico Evaluations

New Synthetic Compounds from Ugi Reaction More Effectively Inhibit Enzymes Targeted in Diabetes Treatment Than Positive Control Acarbose: In Vitro and In Silico Evaluations

by satcit

https://pubmed.ncbi.nlm.nih.gov/38117275

New synthetic compounds derived from a four-component Ugi reaction exhibit enhanced inhibition of α-glucosidase and α-amylase enzymes, potential targets for diabetes treatment, compared to the positive control acarbose, as shown by in vitro and in silico evaluations.

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