Genetic Variant Associated with Decreased Lung Cancer Risk in Smokers: rs56113850 in the CYP2A6 Gene Involved in Tobacco Carcinogen Metabolism with Impact from Smoking Intensity.

https://pubmed.ncbi.nlm.nih.gov/38117513

The genetic variant rs56113850 in the CYP2A6 gene, which metabolizes tobacco carcinogens, is significantly associated with decreased lung cancer risk among smokers, and smoking intensity mediates this genetic effect.