“Haploid Genetic Screening Identifies Dyrk1a as Repressor of Totipotency in Trophectoderm Specification”

https://pubmed.ncbi.nlm.nih.gov/38117886

This study used haploid genetic screening to identify Dyrk1a as a repressor of totipotency in trophectoderm specification, and found that Dyrk1a-null embryonic stem cells exhibit totipotent developmental abilities.