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https://pubmed.ncbi.nlm.nih.gov/38093128
This study suggests that immunocompetent mice can be used as a model for preclinical studies of mRNA vaccine immunogenicity, as their MHC-I is capable of presenting SARS-CoV-2 S-protein peptides that are highly affine for human MHC-I and have been confirmed to be immunogenic in COVID-19 patients.