“Kinase BUB1 identified as direct MYB target in adenoid cystic carcinoma: pharmacological inhibition causes synthetic lethality in patient-derived cells and organoids”

https://pubmed.ncbi.nlm.nih.gov/38112379

The study identifies the kinase BUB1 as a direct target of the oncogenic transcription factor MYB in adenoid cystic carcinoma, and its pharmacological inhibition causes synthetic lethality in patient-derived cells and organoids.