“IsdB Protein in Staphylococcus Aureus: A Virulence Factor Impacting Vaccine Development”

https://pubmed.ncbi.nlm.nih.gov/38112465

The IsdB protein in Staphylococcus aureus, previously considered only for its role in iron acquisition, also serves as a virulence factor by inducing a proinflammatory response via the TLR4-NLRP3-caspase-1 inflammasome cascade, which could impact vaccine development against this pathogen.