“Novel Method for Synthesizing Chiral β-Amino Alcohols and Their Transformation into Heterocycles”

https://pubmed.ncbi.nlm.nih.gov/38112554

This study describes a new method for synthesizing chiral β-amino alcohols using a Brønsted-acid-catalyzed desymmetrization of 1,3-diols with alkynes, which can be further transformed into chiral N-containing heterocycles.