“Coarse-Grained Modeling Identifies Excipient Characteristics for Protein Cryoprotection in Biotherapeutic Formulations”

https://pubmed.ncbi.nlm.nih.gov/38113509

This study used coarse-grained molecular dynamics modeling to examine how 41 excipients interact with a model protein, human serum albumin, and identified excipient characteristics that may prevent aggregation and improve cryoprotection in protein biotherapeutic formulations.