“Rapid ASH2L Degradation Using PROTAC System Causes Sequential, Delayed Deregulation of Histone Marks, Chromatin Accessibility, and Gene Expression”

https://pubmed.ncbi.nlm.nih.gov/38114530

Rapid degradation of the chromatin-modifying protein ASH2L using a PROTAC system leads to a sequential and delayed deregulation of histone marks, chromatin accessibility, and gene expression.