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https://pubmed.ncbi.nlm.nih.gov/38115142
The study found that the proportion of multidrug-resistant organisms (MDROs) in patients with postoperative peritonitis increased from 1999 to 2019, leading to a decrease in the adequacy of empirical antibiotic therapy, particularly for those receiving piperacillin/tazobactam or imipenem/cilastatin combined with vancomycin.