Sheep Bone Tissue’s Acidic Osteoid Organizes in Cholesteric Liquid-Crystal Geometry: Implications for Collagen Fibril Self-Assembly.

https://pubmed.ncbi.nlm.nih.gov/38115757

In sheep, acidic osteoid in the non-fibrillar region of bone tissue organizes in a cholesteric liquid-crystal geometry, potentially driving the self-assembly of collagen fibrils in a plywood pattern during osteoblast-mediated bone formation.