“Long-term Inactivation of Huntingtin in Adult Neurons Using Adeno-Associated Delivery System and KamiCas9 Gene-Editing Technology Is Well Tolerated”

https://pubmed.ncbi.nlm.nih.gov/38116140

Long-term inactivation of wild-type huntingtin in adult striatal and projection neurons through a commonly used adeno-associated delivery system and the self-inactivating KamiCas9 gene-editing system is well tolerated and does not induce behavioral deficits or cellular toxicity.