“Skin-lightening compounds’ impact on hyperpigmentation by targeting interleukin-6, endothelin-1, and melanocyte dendricity”

https://pubmed.ncbi.nlm.nih.gov/38116639

This study suggests that the skin-lightening compounds niacinamide, tranexamic acid, and sucrose laurate/dilaurate mixture may reduce hyperpigmentation by suppressing the release of interleukin-6 and endothelin-1 from epidermal keratinocytes and/or inhibiting melanocyte dendricity.