“Unbiased Molecular Dynamics Simulations Decipher Allosteric Regulation of Oncogenic K-Ras4B Protein in Membrane Interactions”

https://pubmed.ncbi.nlm.nih.gov/38116743

The abstract describes a study that uses unbiased molecular dynamics simulations and four complementary analytical approaches to decipher the allosteric regulation of the oncogenic protein K-Ras4B, revealing how membrane interactions and GTP cleavage influence its allosteric communication pathways and hotspots.