“Novel Enzyme-Activated Probe and Photosensitizer Achieves Complete Tumor Suppression in Mice with Single Treatment”

https://pubmed.ncbi.nlm.nih.gov/38116827

A novel multi-effect enzyme-activated near-infrared probe and photosensitizer show over 2000-fold enrichment in ALP-overexpressed tumor cells, enabling complete tumor suppression in mice even with a single photodynamic therapy treatment.