“Enhancing Crocetin Dissolution and Bioavailability through Ternary Solid Dispersion Formulation using Ball Milling”

https://pubmed.ncbi.nlm.nih.gov/38117406

This study developed a ternary solid dispersion formulation of crocetin using soluplus and meglumine as carriers, prepared by ball milling, to enhance its in vitro dissolution and in vivo oral bioavailability, offering potential benefits for its commercial production and future clinical applications.