“IL-1α Signaling, Antigen-Presenting Cells, and T Cells Involved in Pemphigus Vulgaris Pathogenesis and Glucocorticoid Treatment Effects”

https://pubmed.ncbi.nlm.nih.gov/38117802

This study used single-cell RNA sequencing and immune repertoire analysis to reveal that the IL-1α signaling pathway, myeloid antigen-presenting cells, inflammatory CD8+ resident memory T cells, and dysfunctional CD4+ regulatory T cells are involved in pemphigus vulgaris pathogenesis, and glucocorticoid treatment significantly affects monocytes and mucosal-associated invariant T cells.