“Autoreactive T Cells in Monogenic Autoimmune Disease IPEX Originate from Effector and Regulatory T Cells”

https://pubmed.ncbi.nlm.nih.gov/38117899

In patients with the monogenic autoimmune disease IPEX, autoreactive T cells originate from both effector T cells and regulatory T cells, which can lose their phenotypic and functional markers, leading to immune dysregulation.