“Novel DNA-PK Inhibitor, Compound 31t, Shows Potent and Selective Inhibition with Promising Anti-Cancer Properties”

https://pubmed.ncbi.nlm.nih.gov/38117951

The abstract reports the discovery and optimization of a new DNA-PK inhibitor, compound 31t, which shows potent and selective inhibition of DNA-PK, favorable pharmacokinetic properties, and promising cancer cell growth inhibition in xenograft models.