“Modified T7 RNA Polymerase Activated by Sirtuin-Mediated Deacetylation Links Gene Transcription and NAD Availability”

https://pubmed.ncbi.nlm.nih.gov/38117980

Scientists have created a modified T7 RNA polymerase that depends on sirtuin-mediated deacetylation for activity, providing a link between gene transcription and sirtuin expression/NAD availability.