https://pubmed.ncbi.nlm.nih.gov/38117930
A new genetic fusion associated with blood cancer was identified and found to respond to specific drug inhibitors.
https://pubmed.ncbi.nlm.nih.gov/38117929
Folic acid-modified liposomes loaded with sulfasalazine show promising potential for melanoma treatment by targeting drug delivery and effectively inducing ferroptosis in melanoma cells.
https://pubmed.ncbi.nlm.nih.gov/38117928
The abstract discusses the rising incidence of type 1 diabetes in adolescence, likely caused by a combination of genetic and environmental factors, and highlights the need for further research into modifiable risk factors and gene-environment interactions.
https://pubmed.ncbi.nlm.nih.gov/38117927
The abstract reports on the genetic factors of Type 1 Diabetes, estimating that about 50% of the risk is attributed to genes in the MHC region, including HLA loci, and over 90 non-MHC loci have been identified, with most variants affecting gene regulation rather than protein structure, and further research is needed to understand the genetic and environmental underpinnings of distinct phenotypes within the disease spectrum.
https://pubmed.ncbi.nlm.nih.gov/38117926
The genetics of Type 2 Diabetes have been significantly advanced by large-scale genomic studies, but there is still much to learn about the genetic architecture of metabolic phenotypes related to the disease.
https://pubmed.ncbi.nlm.nih.gov/38117925
Monogenic diabetes, caused by single-gene mutations, may account for up to 3% of all diabetes cases in individuals below 35 years old in the US, but its incidence and prevalence in the country have not been systematically studied.
https://pubmed.ncbi.nlm.nih.gov/38117924
Heart disease remains a significant health concern for individuals with type 2 diabetes, but over the past few years, an increasing number of therapies have become available to reduce cardiovascular risk in people with type 2 diabetes.
https://pubmed.ncbi.nlm.nih.gov/38117923
The abstract reports that in 2019, most adults with diabetes in the US had health insurance, but there were disparities in coverage by age, race/ethnicity, and income, and uninsured adults with diabetes had worse healthcare utilization and control of blood glucose and cholesterol compared to those with insurance.
https://pubmed.ncbi.nlm.nih.gov/38117922
This open educational resource textbook, licensed under CC-BY, introduces nursing leadership, management, legal and ethical concepts, interprofessional collaboration, healthcare economics, and self-care for prelicensure nursing students preparing for the NCLEX-RN exam.
https://pubmed.ncbi.nlm.nih.gov/38117921
The National Institute of Diabetes and Digestive and Kidney Diseases’ “Diabetes in America” is a comprehensive, regularly updated digital resource providing epidemiological, public health, clinical research, and clinical trial data on diabetes and related conditions in the United States.