https://pubmed.ncbi.nlm.nih.gov/38117810
The risk of developing diabetes is associated with a lower health-related quality of life in the Indonesian population.
https://pubmed.ncbi.nlm.nih.gov/38117809
The abstract reports a study’s findings that a specific genetic mutation (CYP3A4*1G) is associated with alcohol drinking and related to increased odds of cardiac-vascular and malignant diseases, but not with differences in liver injury or dyslipidemia in individuals with alcohol abuse.
https://pubmed.ncbi.nlm.nih.gov/38117808
This study provides a comprehensive risk assessment approach for oil well blowouts using a Fuzzy Bayesian Network that considers four independent protection layers and Fault Tree Analysis.
https://pubmed.ncbi.nlm.nih.gov/38117807
In patients with structurally normal hearts, the presence of nonischemic fibrosis on cardiovascular magnetic resonance does not predict adverse outcomes, but elevated diffuse microscopic fibrosis, measured by extracellular volume fraction, is associated with increased all-cause mortality.
https://pubmed.ncbi.nlm.nih.gov/38117806
The abstract reports that transferrin receptor is highly expressed in primary and metastatic breast cancer, including after chemotherapy, and that an iron chelator can enhance its expression, suggesting potential for improved targeting of breast cancer using transferrin-conjugated agents.
https://pubmed.ncbi.nlm.nih.gov/38117804
This study introduces a new, multidimensional psychometric assessment of mental flexibility, called “IntellEGO,” to evaluate cognitive, emotional, and behavioral factors in patients with Anorexia Nervosa and Parkinson’s Disease, providing a comprehensive framework for clinicians to assess mental flexibility in various patient populations.
https://pubmed.ncbi.nlm.nih.gov/38117803
This study at Mayo Clinic aims to improve medical decision-making for glioma patients by collecting and analyzing image-localized biopsy samples and multi-parametric MRIs to generate predictive maps of the spatial distribution of tumor cell density and key genetic markers.
https://pubmed.ncbi.nlm.nih.gov/38117802
This study used single-cell RNA sequencing and immune repertoire analysis to reveal that the IL-1α signaling pathway, myeloid antigen-presenting cells, inflammatory CD8+ resident memory T cells, and dysfunctional CD4+ regulatory T cells are involved in pemphigus vulgaris pathogenesis, and glucocorticoid treatment significantly affects monocytes and mucosal-associated invariant T cells.