https://pubmed.ncbi.nlm.nih.gov/38117457
Cavernous malformation in the fourth ventricle can have serious consequences despite appearing insignificant on imaging.
https://pubmed.ncbi.nlm.nih.gov/38117456
Phanerochaete chrysosporium produces higher levels of cellulases and manganese peroxidase enzymes when grown on untreated corn stover, offering a promising solution for sustainable enzyme production using lignocellulosic biomass.
https://pubmed.ncbi.nlm.nih.gov/38117455
Taurine promotes insulin synthesis in mouse pancreatic islet β-cells by enhancing Isl-1 expression through the miR-7a/RAF1/ERK1/2 pathway, as revealed by using miR-7a2 knockout and taurine transporter knockout mouse models.
https://pubmed.ncbi.nlm.nih.gov/38117454
The study finds that decreased ZMIZ1, associated with vitiligo, inhibits melanin production in vitro by regulating mTOR/AKT/GSK-3β-mediated glucose uptake, suggesting a potential therapeutic target.
https://pubmed.ncbi.nlm.nih.gov/38117453
The conversion of Hashimoto thyroiditis to Graves’ disease is a rare but unpredictable phenomenon, with potential clinical predictors including smoking habit, personal/familial history of non-thyroidal autoimmune disorders, and lower TSH levels during the hypothyroid phase.
https://pubmed.ncbi.nlm.nih.gov/38117452
This study presents a Latin-American consensus of 33 recommendations to facilitate the transition into adult life for patients with X-linked hypophosphatemia, aiming to optimize their management and quality of life.
https://pubmed.ncbi.nlm.nih.gov/38117451
The Scale for Ocular motor Disorders in Ataxia (SODA) shows potential as a reliable clinical tool for evaluating ocular motor abnormalities in patients with Multiple System Atrophy (MSA), though some items like ocular misalignment and spontaneous/positional nystagmus may require improvement.
https://pubmed.ncbi.nlm.nih.gov/38117450
A case report suggests that a combination of cerebello-spinal transcranial direct current stimulation and body weight-supported treadmill training may improve gait and ataxia symptoms in a patient with hypertrophic olivary degeneration.
https://pubmed.ncbi.nlm.nih.gov/38117449
A randomized clinical trial found that frequent delivery of large-magnitude financial incentives for HIV viral suppression resulted in significant improvements in viral load during the intervention period, but these effects were not sustained after incentives were discontinued.
https://pubmed.ncbi.nlm.nih.gov/38117448
Rubiscolin-6 analogs have neuroprotective and anti-inflammatory effects in in vitro models, potentially through an antioxidation mechanism and activation of the PI3-K/AKT/mTOR pathway.