https://pubmed.ncbi.nlm.nih.gov/38093390
The study suggests that disruption of the ApoER2-Dab1 signaling pathway, which regulates lipoprotein internalization and the integrity ofactin, microtubules, and synapses, may drive pTau-associated neurodegeneration in human sporadic Alzheimer’s disease.
https://pubmed.ncbi.nlm.nih.gov/38093388
This study reveals that parents’ antibiotic management for their children in Kosovo is unsatisfactory, with a lack of knowledge on side effects, bacterial resistance, and self-medication, necessitating health education and interventions for rational antibiotic use.
https://pubmed.ncbi.nlm.nih.gov/38093387
MRPL48, a mitochondrial ribosomal protein, is a novel prognostic biomarker for hepatocellular carcinoma, with overexpression associated with poorer patient survival and reduced cell proliferation upon knockdown.
https://pubmed.ncbi.nlm.nih.gov/38093385
This study found that a significant proportion of patients with sexually transmitted infection symptoms in southern Ghana use antimicrobials prior to presenting at health facilities, which contributes to the evolution of antimicrobial resistance and may negatively impact the effectiveness of treatment.
https://pubmed.ncbi.nlm.nih.gov/38093384
In Mumbai’s informal settlements, frequent consumption of ultra-processed foods and sugar-sweetened beverages is common among young children, associated with factors such as lower maternal education, frequent maternal consumption, and proximity to stores, highlighting the need for early childhood nutrition interventions addressing unhealthy food and drink consumption.
https://pubmed.ncbi.nlm.nih.gov/38093383
During the COVID-19 pandemic, the proportion of injury-related visits to pediatric emergency departments increased compared to the same period in 2019, with changes in the mechanisms of injury and differences in racial and payor demographics.
https://pubmed.ncbi.nlm.nih.gov/38093381
This study is a multicenter, open-label, randomized controlled non-inferiority trial aimed at comparing the diagnostic accuracy of dry suction and wet suction techniques in solid pancreatic lesions using 22G Franseen needles and determining the optimal number of passes required for EUS-FNB.