https://pubmed.ncbi.nlm.nih.gov/38093330
This abstract suggests that further research is needed to understand how spinal astrocytes and their perisynaptic astrocytic processes contribute to pathological pain through cell adhesion molecules and chemical signaling.
https://pubmed.ncbi.nlm.nih.gov/38093329
This review discusses how aging affects the ovarian stromal microenvironment and suggests potential strategies to improve ovarian function by targeting the perifollicular environment.
https://pubmed.ncbi.nlm.nih.gov/38093327
The study suggests that supplementation with a high-GABA-producing Lactobacillus plantarum strain may help alleviate essential tremor symptoms by increasing GABA levels in the brain and reducing inflammation, pointing to a potential microbial role in the disorder’s pathogenesis.
https://pubmed.ncbi.nlm.nih.gov/38093326
The interaction between childhood trauma and the TPH2 rs7305115 gene polymorphism may have specific and long-term structural effects on brain gray matter volume, potentially leading to altered cognitive and emotional processes involving the parahippocampal gyrus and thalamus.
https://pubmed.ncbi.nlm.nih.gov/38093325
The study found that referral to an epilepsy center for presurgical diagnosis significantly improves the accuracy of identifying epileptogenic lesions in patients with drug-resistant focal epilepsy, leading to better outcomes after surgery.
https://pubmed.ncbi.nlm.nih.gov/38093324
This study developed an AI-driven molecular generation method that considers patent status, enabling the creation of novel drug-like compounds with high patent potential, thereby improving efficiency in drug development.
https://pubmed.ncbi.nlm.nih.gov/38093323
The study developed the “Engaging with Purpose Patient Engagement Framework” based on a Twitter analysis of community perspectives, identifying respect, support, collaboration, inclusivity, and impact as five key pillars of meaningful patient engagement.
https://pubmed.ncbi.nlm.nih.gov/38093322
This study found that Iranian sulfur mustard survivors have varying healthcare utilization and expenditures depending on age, socioeconomic status, and location, with a pro-rich inequity and higher usage among the elderly, and suggests that health policies should address these disparities.