https://pubmed.ncbi.nlm.nih.gov/38117950
The hydrophilic surface of nanoscaled titanium oxide layer on 3D-printed dental implants enhances blood clotting and promotes quick osseointegration.
https://pubmed.ncbi.nlm.nih.gov/38117948
Researchers have discovered and characterized a potent and selective PIKfyve kinase inhibitor, L22, which induces methuosis-associated cell death in HeLa and MDA-MB-231 cells, and demonstrates significant tumor growth inhibition in a HeLa xenograft model without toxicity.
https://pubmed.ncbi.nlm.nih.gov/38117946
Researchers have developed a versatile method for creating hierarchically structured nanocomposites with controlled placement of multiple inorganic fillers within polymer matrices, enabling new opportunities for advanced materials in various fields.
https://pubmed.ncbi.nlm.nih.gov/38117945
This study used machine learning models to analyze the formation of nucleation mode particles, a type of ultrafine particle, in a coastal city and found that UV, H2SO4, LOOMs, temperature, and O3 were the primary factors influencing their concentration.
https://pubmed.ncbi.nlm.nih.gov/38117944
A diruthenium compound with formamidinate ligands effectively inhibits Amyloid-β aggregation and reduces its cytotoxicity, highlighting its potential as a neurodrugs for managing Alzheimer’s disease.
https://pubmed.ncbi.nlm.nih.gov/38117943
This study developed and validated a faster, more efficient, and accessible method for analyzing amino acids in ruminant feeds, tissue, and milk using isotope dilution Z-HILIC coupled with electrospray ionization triple quadrupole LC-MS/MS.
https://pubmed.ncbi.nlm.nih.gov/38117941
This computational study uses density functional theory and the activation strain model to explore the pathways for dihydrogen activation and hydrogenation of multiple bonds by pyramidalized boron-based frustrated Lewis Pairs, finding a synchronized, asynchronous liberation of activated dihydrogen and a co-operative double hydrogen-transfer mechanism.