https://pubmed.ncbi.nlm.nih.gov/38116768
Steroid sulfates and glucuronides, produced in the human liver, play crucial roles in controlling steroid hormone levels, possessing unique biological activities and affecting gene expression.
https://pubmed.ncbi.nlm.nih.gov/38116768
Steroid sulfates and glucuronides, produced in the human liver, play crucial roles in controlling steroid hormone levels, possessing unique biological activities and affecting gene expression.
https://pubmed.ncbi.nlm.nih.gov/38116767
The nutritional value of most gluten-free products is low, with high energy, fat, carbohydrate, and sugar content and low fiber and protein content, making the use of Front-of-Pack labeling Nutri-score helpful in distinguishing the nutritional value of these products.
https://pubmed.ncbi.nlm.nih.gov/38116766
The study found that chelating Co(II), Cu(II), and Zn(II) ions to quercetin may enhance its antioxidant activity and SARS-CoV-2 main protease inhibition, as shown through DFT, molecular docking, molecular dynamics simulations, and ADMET analysis.
https://pubmed.ncbi.nlm.nih.gov/38116764
The abstract suggests that certain phytochemicals, including Isohydnocarpin, Chitranone, and 1-Hydroxyrutaecarpine, have the potential to inhibit interleukin-8 (IL-8) and show promising anticancer properties, according to in silico findings and molecular dynamics analyses.
https://pubmed.ncbi.nlm.nih.gov/38116763
This study trains convolutional neural networks to accurately detect lymphatic invasion in gastric cancer using a hard negative mining approach in a weakly labeled dataset, improving classification performance and overcoming the scarcity of annotated data.
https://pubmed.ncbi.nlm.nih.gov/38116762
The abstract describes a new method that uses Deep ResUnet and Efficientnet to accurately segment and classify Alzheimer’s disease in brain MRI scans, achieving 99.31% and 99.38% accuracy on Kaggle and ADNI datasets, respectively.
https://pubmed.ncbi.nlm.nih.gov/38116761
This study investigates how radiative and nonradiative damping effects influence the bandwidth of quantized surface plasmons in nanoparticles, and identifies optimum parameters for achieving minimal damping, relevant for advanced sensing and medical applications.
https://pubmed.ncbi.nlm.nih.gov/38116760
This study used integrated metabolomics and transcriptomics analyses to investigate metabolic responses to TGEV infection in porcine intestinal epithelial cells, and found that activation of the AMPK signalling pathway inhibits TGEV replication.
https://pubmed.ncbi.nlm.nih.gov/38116759
This review discusses how the type VIIb secretion system (T7SSb) in Bacillota bacteria mediates interbacterial competition through the secretion of antibacterial toxins targeted at closely related strains.