https://pubmed.ncbi.nlm.nih.gov/38116176
The synthetic CB2R agonist, PM289, improves blood-brain barrier function, decreases inflammation, and enhances endothelial repair in a mouse model of traumatic brain injury.
https://pubmed.ncbi.nlm.nih.gov/38116175
The abstract reports on a letter to the editor discussing Japan’s emergency approval system for medical products during the COVID-19 pandemic, with potential conflicts of interest declared for two of the authors.
https://pubmed.ncbi.nlm.nih.gov/38116174
Intracardiac echocardiography shows promise as a real-time, multi-angle imaging modality that can improve the safety and efficiency of left atrial appendage closure in nonvalvular atrial fibrillation patients.
https://pubmed.ncbi.nlm.nih.gov/38116173
This study used quantile regression to identify risk factors for high blood glucose levels among Bangladeshi individuals, finding that hypertensive disease, overweight/obese BMI, higher economic status, reduced physical activity, and older age contribute to the development of diabetes mellitus.
https://pubmed.ncbi.nlm.nih.gov/38116172
The abstract discusses the challenges and strategies for improving the healthcare system in Afghanistan, focusing on infectious diseases such as tuberculosis, malaria, HIV, COVID-19, measles, hepatitis, and cholera, and highlights the need for comprehensive approaches to address these issues.
https://pubmed.ncbi.nlm.nih.gov/38116171
This study found that up to 8% of human-generated scientific abstracts were mistakenly identified as AI-generated by an AI text detection tool, highlighting the limitations of such detection tools.
https://pubmed.ncbi.nlm.nih.gov/38116170
This study found that stable single and double lung transplant recipients who had undergone transplantation for interstitial lung disease had similar respiratory resistance but worse reactance in single lung transplant recipients, suggesting that elastic properties contribute to the pathophysiology of reduced peak spirometry in this group.
https://pubmed.ncbi.nlm.nih.gov/38116169
This study implemented and trained working memory architectures on an industrial robot using a user-centered approach, finding that considering users’ views contributes to positive robot navigation perception and users’ experience with robots is crucial for a positive human-robot interaction.
https://pubmed.ncbi.nlm.nih.gov/38116168
New thiadiazole derivatives, including compound 14, show promising anti-cancer properties by inhibiting VEGFR-2, promoting apoptosis, and reducing cancer cell migration, highlighting their potential as leads for developing anticancer drugs.
https://pubmed.ncbi.nlm.nih.gov/38116167
In this study, it was found that thyroid nodules with a telomerase reverse transcriptase promoter (TERT) mutation, specifically those that are cytologically indeterminate, have a high risk of malignancy (84%). However, there is no significant difference in malignancy rate between isolated TERT mutations and TERT + RAS co-mutated ITNs, and the histopathology risk description and oncologic outcomes for most TERT mutated ITNs are unknown. Further data is needed to determine if TERT mutated ITNs should be treated aggressively.