https://pubmed.ncbi.nlm.nih.gov/38115214
Aesthetic Plastic Surgery National Databank reported 2.3 million procedures performed in the US in 2022, a 4% increase from the previous year.
https://pubmed.ncbi.nlm.nih.gov/38115213
This study suggests that monitoring changes in fluorescence intensity can effectively indicate the various stages of the Maillard reaction process for complex protein hydrolysates, as it correlates with the degradation of certain compounds and the formation of browning melanoidin.
https://pubmed.ncbi.nlm.nih.gov/38115212
This review discusses the development and advantages of microfluidic blood typing devices, which offer easy, rapid, low-power, and potentially decentralized blood typing, but also highlights their inherent challenges and the importance of integrating digital technologies for long-term sustainability.
https://pubmed.ncbi.nlm.nih.gov/38115210
Genome-wide DNA methylation analysis has identified prognostic CpG site markers that can help predict longer survival times in dogs with multicentric high-grade B-cell lymphoma treated with CHOP chemotherapy.
https://pubmed.ncbi.nlm.nih.gov/38115209
This phase 1 study found that the anti-interleukin-33 antibody tozorakimab was safe, well-tolerated, and demonstrated target engagement in healthy adults and patients with chronic obstructive pulmonary disease, supporting its further clinical development.
https://pubmed.ncbi.nlm.nih.gov/38115208
This phase I study found that combining pembrolizumab (PD-1 inhibitor) with either itacitinib (JAK1 inhibitor) or parsaclisib (PI3Kδ inhibitor) in patients with advanced solid tumors showed limited clinical activity and little effect on T-cell infiltration in the tumor, and thus does not support continued development of these combinations.
https://pubmed.ncbi.nlm.nih.gov/38115207
The burden of perianal disease and perianal surgery rates remain high in Crohn’s disease patients, despite increased use of immunosuppressives and biologics over the last four decades.