https://pubmed.ncbi.nlm.nih.gov/38114479
The cytosolic DNA sensor cGAS in airway epithelium protects against acute lung injury by regulating inflammatory responses through a non-canonical cGAS-CREB pathway.
https://pubmed.ncbi.nlm.nih.gov/38114478
Scientists have significantly reduced the spread in optical emission frequencies of telecom-wavelength spin-active quantum emitters in isotopically-engineered silicon carbide, paving the way for their use in scalable quantum networks.
https://pubmed.ncbi.nlm.nih.gov/38114477
A diagnostic model combining plasma cell-free DNA 5-hydroxymethylcytosine sequencing and low-pass whole genome sequencing shows promising results for non-invasive early detection of esophageal cancer.
https://pubmed.ncbi.nlm.nih.gov/38114475
A machine learning model using only electronic health record data from a sepsis hospitalization can predict the risk of developing trauma- and stressor-related disorders in the year following discharge.
https://pubmed.ncbi.nlm.nih.gov/38114474
This study integrates single-cell, spatial, and in situ analysis to map the tumor microenvironment in breast cancer, revealing molecular differences between tumor regions, identifying biomarkers for invasive carcinoma, and highlighting the power of technology integration in oncology research.
https://pubmed.ncbi.nlm.nih.gov/38114473
The communication between radiosensitive and radioresistant esophageal cancer cells modulates their radiosensitivity, and changes in let-7a and IL-6 levels during radiotherapy may predict treatment response.
https://pubmed.ncbi.nlm.nih.gov/38114472
This global study of frogs and toads shows that color lightness varies with temperature, pathogen pressure, and UVB radiation, indicating its importance for thermoregulation, pathogen resistance, and UVB protection.
https://pubmed.ncbi.nlm.nih.gov/38114471
NEMO, a protein previously known for regulating immune responses, also plays a critical role in the clearance of misfolded proteins, such as α-synuclein, through autophagy, and its deficiency can lead to neurodegenerative disorders.
https://pubmed.ncbi.nlm.nih.gov/38114470
This study emphasizes the importance of incorporating an anticolonial perspective in engineering education and practice to acknowledge and address the colonial legacy in contemporary science and technology, and to reframe technological innovation in light of neocolonial extraction and exploitation.