https://pubmed.ncbi.nlm.nih.gov/38113455
Scientists have developed a new ratiometric, dual-fluorophore calcium sensor using a fast-maturing red LSSmApple fluorophore for improved imaging and quantitative analysis in yeast.
https://pubmed.ncbi.nlm.nih.gov/38113455
Scientists have developed a new ratiometric, dual-fluorophore calcium sensor using a fast-maturing red LSSmApple fluorophore for improved imaging and quantitative analysis in yeast.
https://pubmed.ncbi.nlm.nih.gov/38113454
This study describes a new electrochemical method for synthesizing tetrasubstituted 2,3-allenoates using propargylic alcohols, CO2, and TMSCHN2, which allows for the incorporation of an external ester group into the allene system.
https://pubmed.ncbi.nlm.nih.gov/38113453
The MiniMed 780G system helps people with type 1 diabetes spend over 48% of their time in a tight glucose range (70-140 mg/dL), and consistent use of optimal settings can further increase this time, suggesting a treatment goal of over 50%.
https://pubmed.ncbi.nlm.nih.gov/38113452
This study developed a novel ratiometric fluorescent probe based on aptamer conjugates for precise imaging of therapy-induced cancer senescence, targeting multiple senescence-associated markers at both cellular and subcellular levels for spatiotemporally specific imaging.
https://pubmed.ncbi.nlm.nih.gov/38113451
This study characterizes a diamond-like carbon film and finds it has a combination of sp2 and sp3 carbon with oxygen-containing OH groups on the surface, and shows significant adsorption of a surfactant from water solutions, suggesting its potential as an anti-wear system.
https://pubmed.ncbi.nlm.nih.gov/38113448
This study reports a new organocatalytic method for stereospecific Appel reaction, achieving high yields, enantiospecificities, and enantiomeric ratios using low catalyst loadings and environmentally friendly reagents.
https://pubmed.ncbi.nlm.nih.gov/38113447
ELISL, a new bioinformatics tool using protein sequence embeddings and omics data, predicts synthetic lethality in cancer genes with improved robustness and success in identifying therapeutic targets.