https://pubmed.ncbi.nlm.nih.gov/38112999
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https://pubmed.ncbi.nlm.nih.gov/38113000
The abstract reviews recent findings on how the N6-methyladenosine (m6A) modification in mRNA, a reversible modification found in over 7000 human genes, plays context-dependent roles in solid tumor development, progression, and immunity, and can impact sensitivity to cancer therapies.
https://pubmed.ncbi.nlm.nih.gov/38112998
RNA modifications, particularly N6-methyladenosine, play crucial roles in shaping cancer stem cell behavior, influencing gene expression programs that drive stem-like properties, microenvironment adaptation, metastatic potential, and drug resistance.
https://pubmed.ncbi.nlm.nih.gov/38112997
RNA modifications, particularly N6-methyladenosine, play crucial roles in cancer metabolic reprogramming and shaping the tumor microenvironment, and targeting these modifications shows promise as a therapeutic approach for anti-tumor treatment.
https://pubmed.ncbi.nlm.nih.gov/38112994
This field study found that the most commonly purchased honey bee probiotic in the US, SuperDFM-HoneyBee™, was not effective in restoring the honey bee gut microbiota after antibiotic treatment.