https://pubmed.ncbi.nlm.nih.gov/38117276
The protein CHTOP promotes inflammation in microglia cells by regulating the expression of both inflammation- and cell metabolism-related genes.
https://pubmed.ncbi.nlm.nih.gov/38117275
New synthetic compounds derived from a four-component Ugi reaction exhibit enhanced inhibition of α-glucosidase and α-amylase enzymes, potential targets for diabetes treatment, compared to the positive control acarbose, as shown by in vitro and in silico evaluations.
https://pubmed.ncbi.nlm.nih.gov/38117274
The abstract reports a study in Morocco that found a high prevalence of Blastocystis sp. infection using PCR diagnosis, and a significant association between infection and abdominal pain, while direct examination and culture methods showed lower sensitivity.
https://pubmed.ncbi.nlm.nih.gov/38117272
Spiroplasma infection in Glossina tachinoides tsetse flies significantly reduces the density of trypanosomes, suggesting a potential role in reducing trypanosome transmission and associated risks during sterile insect technique implementation.
https://pubmed.ncbi.nlm.nih.gov/38117271
This abstract describes the discovery and classification of 13 new species of parasitic flatworms (Dactylogyridae) found on marine fish in Moreton Bay, Queensland, Australia, and the proposal of two new genera, Ecnomotrema and Pleuronectitrema.
https://pubmed.ncbi.nlm.nih.gov/38117270
The special pair of Photosystem II reaction centers exhibits nonconservative circular dichroism due to short-range effects causing effective rotation of electric transition dipole moments.
https://pubmed.ncbi.nlm.nih.gov/38117269
This commentary discusses a study evaluating the use of rotational thromboelastometry as a diagnostic tool for periprosthetic joint infection, suggesting its potential as a readily available aid in diagnosis.
https://pubmed.ncbi.nlm.nih.gov/38117267
The study finds that increasing CSF1 to expand tissue macrophages can transform systemic lipid and carbohydrate metabolism, potentially providing a novel approach for managing metabolic syndrome.
https://pubmed.ncbi.nlm.nih.gov/38117266
Monocytes from pregnant women exhibit altered metabolism and enhanced efferocytosis, resembling the immunometabolic phenotype of monocytes treated in vitro with conditioned media from first trimester trophoblast cells, indicating that trophoblast cells contribute to monocyte functional shaping during pregnancy.